Graft ischemia post cell transplantation to the brain: Glucose deprivation as the primary driver of rapid cell death

Graft ischemia post cell transplantation to the brain: Glucose deprivation as the primary driver of rapid cell death

Replacing cells lost during the progression of neurodegenerative disorders holds potential as a therapeutic strategy. Unfortunately, the majority of cells die post-transplantation, which creates logistical and biological challenges for cell therapy approaches. The cause of cell death is likely to be...

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Bibliographic Details
Main Authors: Abrar Hakami, Sebastiano Antonio Rizzo, Oliver J.M. Bartley, Rachel Hills, Sophie V. Precious, Timothy Ostler, Marija Fjodorova, Majed Alghamdi, Anne E. Rosser, Emma L. Lane, Thomas E. Woolley, Mariah J. Lelos, Ben Newland
Format: Article
Language:English
Published: Elsevier 2025-03-01
Series:Neurotherapeutics
Subjects:
Cell transplantation
Ischemia
Hypoxia
Glucose
Cell survival
Online Access:http://www.sciencedirect.com/science/article/pii/S1878747924002058

Internet

http://www.sciencedirect.com/science/article/pii/S1878747924002058

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