G Protein-Coupled Receptor 43 Modulates Neutrophil Recruitment during Acute Inflammation.

Fermentation of dietary fibre in the gut yields large amounts of short chain fatty acids (SCFAs). SCFAs can impart biological responses in cells through their engagement of 'metabolite-sensing' G protein-coupled receptors (GPCRs). One of the main SCFA receptors, GPR43, is highly expressed...

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Bibliographic Details
Main Authors: Marjon E Kamp, Raymond Shim, Alyce J Nicholls, Ana Carolina Oliveira, Linda J Mason, Lauren Binge, Charles R Mackay, Connie H Y Wong
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5033414?pdf=render