Dosing Pattern and Early Cumulative Dose of Liposomal Irinotecan in Metastatic Pancreatic Cancer: A Real-World Multicenter Study

Dosing Pattern and Early Cumulative Dose of Liposomal Irinotecan in Metastatic Pancreatic Cancer: A Real-World Multicenter Study

IntroductionThis multicenter, real-world cohort study aimed to evaluate the effectiveness of early cumulative dose administration and dosing pattern of liposomal irinotecan plus fluorouracil/leucovorin (nal-IRI+5-FU/LV) in patients with gemcitabine-refractory metastatic pancreatic ductal adenocarcin...

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Main Authors: Yung-Yeh Su, Nai-Jung Chiang, Chung-Pin Li, Chia-Jui Yen, Shih-Hung Yang, Wen-Chi Chou, Jen-Shi Chen, Tai-Jan Chiu, Yen-Yang Chen, Shih-Chang Chuang, Li-Yuan Bai, Chang-Fang Chiu, Cheng-Ming Peng, De-Chuan Chan, Sz-Chi Chiu, Yi-Hsin Yang, Yan-Shen Shan, Li‐Tzong Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Oncology
Subjects:
pancreatic cancer
nal-IRI
dose intensity
dose escalation strategy
real world
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.800842/full

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https://www.frontiersin.org/articles/10.3389/fonc.2022.800842/full

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