Integrated miRNA/cytokine/chemokine profiling reveals severity-associated step changes and principal correlates of fatality in COVID-19

Integrated miRNA/cytokine/chemokine profiling reveals severity-associated step changes and principal correlates of fatality in COVID-19

Summary: Inflammatory cytokines and chemokines (CC) drive COVID-19 pathology. Yet, patients with similar circulating CC levels present with different disease severity. Here, we determined 171 microRNAomes from 58 hospitalized COVID-19 patients (Cohort 1) and levels of 25 cytokines and chemokines (CC...

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Bibliographic Details
Main Authors: Julie C. Wilson, David Kealy, Sally R. James, Tobias Plowman, Katherine Newling, Christopher Jagger, Kara Filbey, Elizabeth R. Mann, Joanne E. Konkel, Madhvi Menon, Sean B. Knight, Angela Simpson, Aliya Prihartadi, Greg Forshaw, Neil Todd, David R.A. Yates, John R. Grainger, Tracy Hussell, Paul M. Kaye, Nathalie Signoret, Dimitris Lagos
Format: Article
Language:English
Published: Elsevier 2022-01-01
Series:iScience
Subjects:
Health sciences
Clinical finding
Complex system biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004221016424

Internet

http://www.sciencedirect.com/science/article/pii/S2589004221016424

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