Characterization of Extracellular Vesicles Secreted in Lentiviral Producing HEK293SF Cell Cultures

Characterization of Extracellular Vesicles Secreted in Lentiviral Producing HEK293SF Cell Cultures

Lentiviral vectors (LVs) are a powerful tool for gene and cell therapy and human embryonic kidney cells (HEK293) have been extensively used as a platform for production of these vectors. Like most cells and cellular tissues, HEK293 cells release extracellular vesicles (EVs). EVs released by cells sh...

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Bibliographic Details
Main Authors: Aline Do Minh, Alexandra T. Star, Jacek Stupak, Kelly M. Fulton, Arsalan S. Haqqani, Jean-François Gélinas, Jianjun Li, Susan M. Twine, Amine A. Kamen
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Viruses
Subjects:
extracellular vesicles
enveloped viruses
lentiviral vectors
exosome
proteomics
lipidomics
Online Access:https://www.mdpi.com/1999-4915/13/5/797

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https://www.mdpi.com/1999-4915/13/5/797

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