High in Vitro Anti-Tumor Efficacy of Dimeric Rituximab/Saporin-S6 Immunotoxin

The anti-CD20 mAb Rituximab has revolutionized lymphoma therapy, in spite of a number of unresponsive or relapsing patients. Immunotoxins, consisting of toxins coupled to antibodies, are being investigated for their potential ability to augment Rituximab efficacy. Here, we compare the anti-tumor eff...

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Bibliographic Details
Main Authors: Massimo Bortolotti, Andrea Bolognesi, Maria Giulia Battelli, Letizia Polito
Format: Article
Language:English
Published: MDPI AG 2016-06-01
Series:Toxins
Subjects:
Online Access:http://www.mdpi.com/2072-6651/8/6/192