Analytical validation and clinical utilization of K-4CARE™: a comprehensive genomic profiling assay with personalized MRD detection

Analytical validation and clinical utilization of K-4CARE™: a comprehensive genomic profiling assay with personalized MRD detection

Background: Biomarker testing has gradually become standard of care in precision oncology to help physicians select optimal treatment for patients. Compared to single-gene or small gene panel testing, comprehensive genomic profiling (CGP) has emerged as a more time- and tissue-efficient method. This...

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Main Authors: Thien-Phuc Nguyen Hoang, Tien Anh Nguyen, Nam H. B. Tran, Van-Anh Nguyen Hoang, Hong Thuy Thi Dao, Vu-Uyen Tran, Yen Nhi Nguyen, Anh Tuan Nguyen, Cam Tu Nguyen Thi, Thanh Thuy Do Thi, Duy Sinh Nguyen, Hoai-Nghia Nguyen, Hoa Giang, Lan N. Tu
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-02-01
Series:Frontiers in Molecular Biosciences
Subjects:
comprehensive genomic profiling
tumor mutational burden
microsatellite instability
minimal residual disease
ctdna (circulating tumor DNA)
targeted therapy
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2024.1334808/full

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https://www.frontiersin.org/articles/10.3389/fmolb.2024.1334808/full

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