Cellular Biogenetic Law and Its Distortion by Protein Interactions: A Possible Unified Framework for Cancer Biology and Regenerative Medicine

Cellular Biogenetic Law and Its Distortion by Protein Interactions: A Possible Unified Framework for Cancer Biology and Regenerative Medicine

The biogenetic law (recapitulation law) states that ontogenesis recapitulates phylogenesis. However, this law can be distorted by the modification of development. We showed the recapitulation of phylogenesis during the differentiation of various cell types, using a meta-analysis of human single-cell...

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Bibliographic Details
Main Authors: Alexander E. Vinogradov, Olga V. Anatskaya
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:International Journal of Molecular Sciences
Subjects:
cell differentiation
gene phylostratigraphy
gene expression
interactome
embryonic stem cells
induced pluripotent stem cells
Online Access:https://www.mdpi.com/1422-0067/23/19/11486

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https://www.mdpi.com/1422-0067/23/19/11486

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