Synthesis, anticancer and molecular docking studies of new class of benzoisoxazolyl-piperidinyl-1, 2, 3-triazoles

Synthesis, anticancer and molecular docking studies of new class of benzoisoxazolyl-piperidinyl-1, 2, 3-triazoles

A small library of hitherto unexplored novel 5-fluorobenzoisoxazolyl-piperidinyl-1, 2, 3-triazole derivatives has been synthesized from 2-azido-fluorobenzoisoxazolyl piperidinyl ethanone and various alkynes in good to excellent yields through a click chemistry approach. Compounds thus synthesized we...

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Bibliographic Details
Main Authors: Govindhan Muniyappan, Subramanian Kathavarayan, Chandrasekar Balachandran, Easwaramoorthi Kalliyappan, Sakkarapalayam M. Mahalingam, Abdul Ajees Abdul Salam, Shin Aoki, Natarajan Arumugam, Abdulrahman I. Almansour, Raju Suresh Kumar
Format: Article
Language:English
Published: Elsevier 2020-12-01
Series:Journal of King Saud University: Science
Subjects:
1,2,3-Triazoles
Click chemistry reaction
Anticancer activity
Molecular docking studies
Online Access:http://www.sciencedirect.com/science/article/pii/S1018364720302809

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http://www.sciencedirect.com/science/article/pii/S1018364720302809

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