Cerebrospinal fluid shotgun proteomics identifies distinct proteomic patterns in cerebral amyloid angiopathy rodent models and human patients

Cerebrospinal fluid shotgun proteomics identifies distinct proteomic patterns in cerebral amyloid angiopathy rodent models and human patients

Abstract Cerebral amyloid angiopathy (CAA) is a form of small vessel disease characterised by the progressive deposition of amyloid β protein in the cerebral vasculature, inducing symptoms including cognitive impairment and cerebral haemorrhages. Due to their accessibility and homogeneous disease ph...

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Bibliographic Details
Main Authors: Marc Vervuurt, Joseph M. Schrader, Anna M. de Kort, Iris Kersten, Hans J. C. T. Wessels, Catharina J. M. Klijn, Floris H. B. M. Schreuder, H. Bea Kuiperij, Jolein Gloerich, William E. Van Nostrand, Marcel M. Verbeek
Format: Article
Language:English
Published: BMC 2024-01-01
Series:Acta Neuropathologica Communications
Subjects:
Cerebral amyloid angiopathy
Cerebrospinal fluid
Shotgun proteomics
Biomarkers
Animal model
Online Access:https://doi.org/10.1186/s40478-023-01698-4

Internet

https://doi.org/10.1186/s40478-023-01698-4

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