Comparison of SHANK3 deficiency in animal models: phenotypes, treatment strategies, and translational implications

Abstract Background Autism spectrum disorder (ASD) is a neurodevelopmental condition, which is characterized by clinical heterogeneity and high heritability. Core symptoms of ASD include deficits in social communication and interaction, as well as restricted, repetitive patterns of behavior, interes...

Full description

Bibliographic Details
Main Authors: Jan Philipp Delling, Tobias M. Boeckers
Format: Article
Language:English
Published: BMC 2021-11-01
Series:Journal of Neurodevelopmental Disorders
Subjects:
Online Access:https://doi.org/10.1186/s11689-021-09397-8