Clinical spectrum and evolution of immune-checkpoint inhibitors toxicities over a decade—a worldwide perspectiveResearch in context

Clinical spectrum and evolution of immune-checkpoint inhibitors toxicities over a decade—a worldwide perspectiveResearch in context

Summary: Background: Immune-checkpoint inhibitors (ICI) have revolutionized cancer treatment by harnessing the immune system but ICI can induce life-threatening immune-related adverse events (irAE) affecting every organ. Methods: We extracted irAE from VigiBase, the international pharmacovigilance...

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Bibliographic Details
Main Authors: Paul Gougis, Floriane Jochum, Baptiste Abbar, Elise Dumas, Kevin Bihan, Bénédicte Lebrun-Vignes, Javid Moslehi, Jean-Philippe Spano, Enora Laas, Judicael Hotton, Fabien Reyal, Anne-Sophie Hamy, Joe-Elie Salem
Format: Article
Language:English
Published: Elsevier 2024-04-01
Series:EClinicalMedicine
Subjects:
Immune checkpoint inhibitors
Immune-related adverse events
Cancer
Pharmacology
Pharmacovigilance
Myotoxicity
Online Access:http://www.sciencedirect.com/science/article/pii/S2589537024001159

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http://www.sciencedirect.com/science/article/pii/S2589537024001159

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