Transcriptional regulation of the anti-inflammatory cytokine IL-10 in acquired immune cells.

Although the major role of the immune response is host defense from a wide range of potentially pathogenic microorganisms, excess immune responses can result in severe host damage. The host thus requires anti-inflammatory mechanisms to prevent reactivity to self. Interleukin-10 (IL-10) is a cytokine...

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Bibliographic Details
Main Authors: Masato eKubo, Yasutaka eMotomura
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-08-01
Series:Frontiers in Immunology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2012.00275/full