RNase E biomolecular condensates stimulate PNPase activity

Abstract Bacterial Ribonucleoprotein bodies (BR-bodies) play an essential role in organizing RNA degradation via phase separation in the cytoplasm of bacteria. BR-bodies mediate multi-step mRNA decay through the concerted activity of the endoribonuclease RNase E coupled with the 3′-5′ exoribonucleas...

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Bibliographic Details
Main Authors: Michael J. Collins, Dylan T. Tomares, Vidhyadhar Nandana, Jared M. Schrader, W. Seth Childers
Format: Article
Language:English
Published: Nature Portfolio 2023-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-39565-w