Dietary ketosis improves circadian dysfunction as well as motor symptoms in the BACHD mouse model of Huntington’s disease

Disturbances in sleep/wake cycles are common among patients with neurodegenerative diseases including Huntington’s disease (HD) and represent an appealing target for chrono-nutrition-based interventions. In the present work, we sought to determine whether a low-carbohydrate, high-fat diet would amel...

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Bibliographic Details
Main Authors: Daniel S. Whittaker, T. Katherine Tamai, Raj S. Bains, Sophia Anne Marie Villanueva, Shu Hon Christopher Luk, Derek Dell’Angelica, Gene D. Block, Cristina A. Ghiani, Christopher S. Colwell
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-11-01
Series:Frontiers in Nutrition
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fnut.2022.1034743/full