Aortic Fibrosis in Insulin-Sensitive Mice with Endothelial Cell-Specific Deletion of <i>Ceacam1</i> Gene

Aortic Fibrosis in Insulin-Sensitive Mice with Endothelial Cell-Specific Deletion of <i>Ceacam1</i> Gene

(1) Background: Mice with global <i>Ceacam1</i> deletion developed plaque-like aortic lesions even on C57BL/6J background in the presence of increased endothelial cell permeability and insulin resistance. Loss of endothelial <i>Ceacam1</i> gene caused endothelial dysfunction...

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Bibliographic Details
Main Authors: Raghd Abu Helal, Harrison T. Muturi, Abraham D. Lee, Wei Li, Hilda E. Ghadieh, Sonia M. Najjar
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:International Journal of Molecular Sciences
Subjects:
insulin resistance
inflammation
oxidative stress
atheroma
fibrosis
fatty streaks
Online Access:https://www.mdpi.com/1422-0067/23/8/4335

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https://www.mdpi.com/1422-0067/23/8/4335

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