MDSCs participate in the pathogenesis of diffuse pulmonary hemorrhage in murine lupus through mTOR-FoxO1 signaling

MDSCs participate in the pathogenesis of diffuse pulmonary hemorrhage in murine lupus through mTOR-FoxO1 signaling

Diffuse pulmonary hemorrhage (DPH) is a common respiratory complication in patients with systemic lupus erythematosus (SLE). Our previous study found that myeloid-derived suppressor cells (MDSCs) have an important role in SLE pathogenesis. In this study, we further examined the role of MDSCs in the...

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Bibliographic Details
Main Authors: Liping Tan, Guoping Shi, Junyu Zhao, Xiaoyu Xia, Dan Li, Saiwen Wang, Jun Liang, Yayi Hou, Huan Dou
Format: Article
Language:English
Published: Elsevier 2022-12-01
Series:Biochemistry and Biophysics Reports
Subjects:
Myeloid-derived suppressor cells
Macrophage
Diffuse pulmonary hemorrhage
Mammalian target of rapamycin
Forkhead box-O1
Systemic lupus erythematosus
Online Access:http://www.sciencedirect.com/science/article/pii/S2405580822001510

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http://www.sciencedirect.com/science/article/pii/S2405580822001510

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