SIRT4 is an independent prognostic factor in bladder cancer and inhibits bladder cancer growth by suppressing autophagy

Abstract Background Nucleosome-localized sirtuin 4 (SIRT4) was found to function as an oncogene and tumor suppressor gene in different tumors. However, the clinical significance of SIRT4 in bladder urothelial carcinoma (BLCA) has not been assessed, nor has the function of SIRT4 in BLCA been analyzed...

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Bibliographic Details
Main Authors: Jie Yin, Guohao Cai, Huaiwen Wang, Weijia Chen, Shan Liu, Guoyu Huang
Format: Article
Language:English
Published: BMC 2023-06-01
Series:Cell Division
Subjects:
Online Access:https://doi.org/10.1186/s13008-023-00091-w