Modifying oncolytic virotherapy to overcome the barrier of the hypoxic tumor microenvironment. Where do we stand?

Abstract Viruses are completely dependent on host cell machinery for their reproduction. As a result, factors that influence the state of cells, such as signaling pathways and gene expression, could determine the outcome of viral pathogenicity. One of the important factors influencing cells or the o...

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Bibliographic Details
Main Authors: Sara Shayan, Arash Arashkia, Kayhan Azadmanesh
Format: Article
Language:English
Published: BMC 2022-11-01
Series:Cancer Cell International
Subjects:
Online Access:https://doi.org/10.1186/s12935-022-02774-w