Integrated metabolic-transcriptomic network identifies immunometabolic modulations in human macrophages

Summary: Macrophages exhibit diverse phenotypes and respond flexibly to environmental cues through metabolic remodeling. In this study, we present a comprehensive multi-omics dataset integrating intra- and extracellular metabolomes with transcriptomic data to investigate the metabolic impact on huma...

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Bibliographic Details
Main Authors: Hung-Jen Chen, Daniel C. Sévin, Guillermo R. Griffith, Johanna Vappiani, Lee M. Booty, Cindy P.A.A. van Roomen, Johan Kuiper, Jeroen den Dunnen, Wouter J. de Jonge, Rab K. Prinjha, Palwinder K. Mander, Paola Grandi, Beata S. Wyspianska, Menno P.J. de Winther
Format: Article
Language:English
Published: Elsevier 2024-09-01
Series:Cell Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124724010921