Optimal target blood pressure in elderly with septic shock (OPTPRESS) trial: study protocol for a randomized controlled trial

Abstract Background Hemodynamic stabilization is a core component in the resuscitation of septic shock. However, the optimal target blood pressure remains debatable. Previous randomized controlled trials suggested that uniformly adopting a target mean arterial pressure (MAP) higher than 65 mmHg for...

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Bibliographic Details
Main Authors: Akira Endo, Kazuma Yamakawa, Takashi Tagami, Yutaka Umemura, Kyosuke Takahashi, Hiroki Nagasawa, Yuichi Araki, Mitsuaki Kojima, Toshiki Sera, Masayuki Yagi, Ryo Yamamoto, Jiro Takahashi, Masaki Nakane, Chikashi Takeda, Chihiro Narita, Satoshi Kazuma, Hiroko Okura, Hiroyuki Takahashi, Takeshi Wada, Shu Tahara, Ayaka Matsuoka, Todani Masaki, Atsushi Shiraishi, Keiichiro Shimoyama, Yuta Yokokawa, Rintaro Nakamura, Hisako Sageshima, Yuichiro Yanagida, Kunihiko Takahashi, Yasuhiro Otomo
Format: Article
Language:English
Published: BMC 2022-09-01
Series:Trials
Subjects:
Online Access:https://doi.org/10.1186/s13063-022-06732-9