Testing the Domino Theory of Gene Loss in Buchnera aphidicola: The Relevance of Epistatic Interactions

The domino theory of gene loss states that when some particular gene loses its function and cripples a cellular function, selection will relax in all functionally related genes, which may allow for the non-functionalization and loss of these genes. Here we study the role of epistasis in determining...

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Bibliographic Details
Main Authors: David J. Martínez-Cano, Gil Bor, Andrés Moya, Luis Delaye
Format: Article
Language:English
Published: MDPI AG 2018-05-01
Series:Life
Subjects:
Online Access:http://www.mdpi.com/2075-1729/8/2/17