Circulating choline and phosphocholine measurement by a hydrophilic interaction liquid chromatography–tandem mass spectrometry

Circulating choline and phosphocholine measurement by a hydrophilic interaction liquid chromatography–tandem mass spectrometry

Background: Given the growing interest in studying the role of choline and phosphocholine in the development and progression of tumor pathology, in this study we describe the development and validation of a fast and robust method for the simultaneous analysis of choline and phosphocholine in human p...

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Bibliographic Details
Main Authors: Giulia Guerra, Francesco Segrado, Patrizia Pasanisi, Eleonora Bruno, Salvatore Lopez, Francesco Raspagliesi, Michela Bianchi, Elisabetta Venturelli
Format: Article
Language:English
Published: Elsevier 2023-11-01
Series:Heliyon
Subjects:
Choline
HILIC HPLC-MS
Human plasma
method validation
Phosphocholine
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844023091296

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http://www.sciencedirect.com/science/article/pii/S2405844023091296

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