Immune-Mediated Systemic Vasculitis as the Proposed Cause of Sudden-Onset Sensorineural Hearing Loss following Lassa Virus Exposure in Cynomolgus Macaques

Immune-Mediated Systemic Vasculitis as the Proposed Cause of Sudden-Onset Sensorineural Hearing Loss following Lassa Virus Exposure in Cynomolgus Macaques

ABSTRACT Lassa virus (LASV) causes a severe, often fatal hemorrhagic disease in regions in Africa where the disease is endemic, and approximately 30% of patients develop sudden-onset sensorineural hearing loss after recovering from acute disease. The causal mechanism of hearing loss in LASV-infected...

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Bibliographic Details
Main Authors: Kathleen A. Cashman, Eric R. Wilkinson, Xiankun Zeng, Anthony P. Cardile, Paul R. Facemire, Todd M. Bell, Jeremy J. Bearss, Carl I. Shaia, Connie S. Schmaljohn
Format: Article
Language:English
Published: American Society for Microbiology 2018-11-01
Series:mBio
Subjects:
Lassa virus
Lassa fever
polyarteritis nodosa
microscopic polyangiitis
vasculitides
autoimmunity
Online Access:https://journals.asm.org/doi/10.1128/mBio.01896-18

Internet

https://journals.asm.org/doi/10.1128/mBio.01896-18

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