EVA1A regulates hematopoietic stem cell regeneration via ER-mitochondria mediated apoptosis

Abstract Excessive protein synthesis upon enhanced cell proliferation frequently results in an increase of unfolded or misfolded proteins. During hematopoietic regeneration, to replenish the hematopoietic system, hematopoietic stem cells (HSCs) are activated and undergo a rapid proliferation. But ho...

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Bibliographic Details
Main Authors: Bo Liu, Yuanyuan Zhou, Qiaofeng Wu, Yuting Fu, Xianli Zhang, Zhenkun Wang, Weiwei Yi, Hu Wang, Zhiyang Chen, Zhangfa Song, Wei Xiong, Yugang Qiu, Weifeng He, Zhenyu Ju
Format: Article
Language:English
Published: Nature Publishing Group 2023-01-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-023-05559-9