Sulfur-mediated chalcogen versus hydrogen bonds in proteins: a see-saw effect in the conformational space

Divalent sulfur (S) forms a chalcogen bond (Ch-bond) via its σ-holes and a hydrogen bond (H-bond) via its lone pairs. The relevance of these interactions and their interplay for protein structure and function is unclear. Based on the analyses of the crystal structures of small organic/organometallic...

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Bibliographic Details
Main Authors: Vishal Annasaheb Adhav, Sanket Satish Shelke, Pananghat Balanarayan, Kayarat Saikrishnan
Format: Article
Language:English
Published: Cambridge University Press 2023-01-01
Series:QRB Discovery
Subjects:
Online Access:https://www.cambridge.org/core/product/identifier/S2633289223000030/type/journal_article