Impact of four times daily dosing of oral treprostinil on tolerability and daily dose achieved in pulmonary hypertension

Oral treprostinil (TRE) is a prostacylin that is approved for the treatment of patients with pulmonary arterial hypertension (PAH). Dosing is approved for two or three times daily (t.i.d.); however, adverse effects, including gastrointestinal-related symptoms, may limit the ability to reach optimal...

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Bibliographic Details
Main Authors: James C. Coons, Cheryl Bunner, David C. Ishizawar, Michael G. Risbano, Belinda Rivera-Lebron, Michael A. Mathier, Stephen Y. Chan, Marc A. Simon
Format: Article
Language:English
Published: Wiley 2017-11-01
Series:Pulmonary Circulation
Online Access:https://doi.org/10.1177/2045893217744512