FYN/TOPK/HSPB1 axis facilitates the proliferation and metastasis of gastric cancer

Abstract Background FYN is a nonreceptor tyrosine kinase that regulates diverse pathological processes. The pro-cancer role of FYN in multiple malignancies has been elucidated. However, the mechanisms that FYN promotes gastric cancer (GC) progression remain largely unknown. Methods In vitro and in v...

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Bibliographic Details
Main Authors: SanFei Peng, YuHan Yin, YiZheng Zhang, Feng Zhu, Ge Yang, Yang Fu
Format: Article
Language:English
Published: BMC 2023-04-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
Online Access:https://doi.org/10.1186/s13046-023-02652-x