Targeting Myeloid-Derived Suppressor Cells in Ovarian Cancer

Myeloid-derived suppressor cells (MDSCs) are a heterogeneous population of immature myeloid cells that exhibit immunosuppressive activity. They also directly stimulate tumor cell proliferation, metastasis, and angiogenesis. In ovarian cancer, there are increased numbers of circulating or tumor-infil...

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Bibliographic Details
Main Authors: Seiji Mabuchi, Tomoyuki Sasano, Naoko Komura
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/10/2/329