Development of a red-shifted photosensitizer for near-infrared photoimmunotherapy of cancer

Development of a red-shifted photosensitizer for near-infrared photoimmunotherapy of cancer

Near-infrared photoimmunotherapy (NIR-PIT) is a recently described method for cancer treatment that utilizes an antibody-conjugated phthalocyanine photosensitizer and NIR light. In NIR-PIT, light of 690 nm wavelength is used to activate a photosensitizer, IR700, while longer-wavelength light penetra...

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Bibliographic Details
Main Authors: Yuto Goto, Kanta Ando, Hideo Takakura, Kohei Nakajima, Masato Kobayashi, Osamu Inanami, Tetsuya Taketsugu, Mikako Ogawa
Format: Article
Language:English
Published: Elsevier 2024-04-01
Series:Journal of Photochemistry and Photobiology
Subjects:
Antibody conjugate
Axial ligand
Near-infrared photoimmunotherapy
Photosensitizer
Red shift
Silicon phthalocyanine
Online Access:http://www.sciencedirect.com/science/article/pii/S2666469024000058

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http://www.sciencedirect.com/science/article/pii/S2666469024000058

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