Genetic factors underlying tacrolimus intolerance after liver transplantation

Genetic factors underlying tacrolimus intolerance after liver transplantation

BackgroundTacrolimus (FK506) is the cornerstone of immunosuppression after liver transplantation (LT), however, clinically, switching from FK506 to cyclosporine (SFTC) is common in LT patients with tacrolimus intolerance. The aim of this study was to investigate the genetic risk of patients with tac...

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Bibliographic Details
Main Authors: Yuan Liu, Rui Wang, Peizhen Wen, Wenbin An, Jinxin Zheng, Tao Zhang, Pengshan Zhang, Haoyu Wang, Fan Zou, Hui Pan, Junwei Fan, Zhihai Peng
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Immunology
Subjects:
CYP3A5
liver transplantation
tacrolimus intolerance
tacrolimus
insulin resistence
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.944442/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.944442/full

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