Evolution of Pfdhps and Pfdhfr mutations before and after adopting seasonal malaria chemoprevention in Nanoro, Burkina Faso

Evolution of Pfdhps and Pfdhfr mutations before and after adopting seasonal malaria chemoprevention in Nanoro, Burkina Faso

Abstract Seasonal Malaria Chemoprevention consisting of monthly administration of amodiaquine/sulfadoxine-pyrimethamine to children aged 3–59 months during the transmission season could promote SP-resistance. Mutations in dihydrofolate reductase (Pfdhfr) and dihydropteroate synthase (Pfdhps) genes w...

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Bibliographic Details
Main Authors: Francis Emmanuel Towanou Bohissou, Paul Sondo, Juliana Inoue, Toussaint Rouamba, Berenger Kaboré, Guétawendé Job Wilfried Nassa, A. Elisée Sié Kambou, Tiampan Edwig Traoré, Victor Asua, Steffen Borrmann, Halidou Tinto, Jana Held
Format: Article
Language:English
Published: Nature Portfolio 2024-10-01
Series:Scientific Reports
Subjects:
Plasmodium falciparum
Pfdhfr
Pfdhps
SMC
Burkina Faso
Online Access:https://doi.org/10.1038/s41598-024-75369-2

Internet

https://doi.org/10.1038/s41598-024-75369-2

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