Trade-offs and constraints in allosteric sensing.

Sensing extracellular changes initiates signal transduction and is the first stage of cellular decision-making. Yet relatively little is known about why one form of sensing biochemistry has been selected over another. To gain insight into this question, we studied the sensing characteristics of one...

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Bibliographic Details
Main Authors: Bruno M C Martins, Peter S Swain
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-11-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC3207937?pdf=render