Microglia/macrophage polarization regulates spontaneous remyelination in intermittent cuprizone model of demyelination

Microglia/macrophage polarization regulates spontaneous remyelination in intermittent cuprizone model of demyelination

Central nervous system (CNS) lesions can repeatedly be de-and remyelinated during demyelinating diseases such as multiple sclerosis (MS). Here, we designed an intermittent demyelination model by 0.3 % Cuprizone feeding in C57/BL6 mice followed by two weeks recovery. Histochemical staining of luxol f...

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Bibliographic Details
Main Authors: Davood Zarini, Parichehr Pasbakhsh, Sina Mojaverrostami, Shiva Amirizadeh, Maedeh Hashemi, Maryam Shabani, Mehrazin Noshadian, Iraj Ragerdi Kashani
Format: Article
Language:English
Published: Elsevier 2024-03-01
Series:Biochemistry and Biophysics Reports
Subjects:
Multiple sclerosis (MS)
Demyelination
Cuprizone
Intermittent
Glial
Macrophage
Online Access:http://www.sciencedirect.com/science/article/pii/S240558082300211X

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http://www.sciencedirect.com/science/article/pii/S240558082300211X

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