Alzheimer’s Amyloid Hypothesis and Antibody Therapy: Melting Glaciers?

The amyloid cascade hypothesis for Alzheimer’s disease is still alive, although heavily challenged. Effective anti-amyloid immunotherapy would confirm the hypothesis’ claim that the protein amyloid-beta is the cause of the disease. Two antibodies, aducanumab and lecanemab, have been approved by the...

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Bibliographic Details
Main Authors: Poul F. Høilund-Carlsen, Abass Alavi, Rudolph J. Castellani, Rachael L. Neve, George Perry, Mona-Elisabeth Revheim, Jorge R. Barrio
Format: Article
Language:English
Published: MDPI AG 2024-03-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/25/7/3892