Minocycline for sporadic and hereditary cerebral amyloid angiopathy (BATMAN): study protocol for a placebo-controlled randomized double-blind trial

Minocycline for sporadic and hereditary cerebral amyloid angiopathy (BATMAN): study protocol for a placebo-controlled randomized double-blind trial

Abstract Background Cerebral amyloid angiopathy (CAA) is a disease caused by the accumulation of the amyloid-beta protein and is a major cause of intracerebral hemorrhage (ICH) and vascular dementia in the elderly. The presence of the amyloid-beta protein in the vessel wall may induce a chronic stat...

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Bibliographic Details
Main Authors: S. Voigt, E. A. Koemans, I. Rasing, E. S. van Etten, G. M. Terwindt, F. Baas, K. Kaushik, A. C. G. M. van Es, M. A. van Buchem, M. J. P. van Osch, M. A. A. van Walderveen, C. J. M. Klijn, M. M. Verbeek, L. van der Weerd, M. J. H. Wermer
Format: Article
Language:English
Published: BMC 2023-06-01
Series:Trials
Subjects:
Cerebral amyloid angiopathy
Minocycline
Dutch-type CAA
Cerebrospinal fluid
7T MRI
Randomized controlled trial
Online Access:https://doi.org/10.1186/s13063-023-07371-4

Internet

https://doi.org/10.1186/s13063-023-07371-4

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