CXCL12/CXCR4 axis triggers the activation of EGF receptor and ERK signaling pathway in CsA-induced proliferation of human trophoblast cells.

INTRODUCTION: Our previous study has demonstrated Cyclosporin A (CsA) promotes the proliferation of human trophoblast cells. Therefore, we further investigate the intracellular signaling pathway involved in the CsA-induced proliferation of human trophoblast cells. METHODS: Enzyme-linked immunosorben...

Full description

Bibliographic Details
Main Authors: Hong-Bo Zhao, Chuan-Ling Tang, Yan-Li Hou, Li-Rong Xue, Ming-Qing Li, Mei-Rong Du, Da-Jin Li
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3407218?pdf=render