Construction and Radiolabeling of Adenovirus Variants that Incorporate Human Metallothionein into Protein IX for Analysis of Biodistribution

Using adenovirus (Ad)-based vectors is a promising strategy for novel cancer treatments; however, current tracking approaches in vivo are limited. The C-terminus of the Ad minor capsid protein IX (pIX) can incorporate heterologous reporters to monitor biodistribution. We incorporated metallothionein...

Full description

Bibliographic Details
Main Authors: Lei Liu, Buck E. Rogers, Natalia Aladyshkina, Bing Cheng, Stephen J. Lokitz, David T. Curiel, J. Michael Mathis
Format: Article
Language:English
Published: SAGE Publications 2014-09-01
Series:Molecular Imaging
Online Access:https://doi.org/10.2310/7290.2014.00022