Construction and Radiolabeling of Adenovirus Variants that Incorporate Human Metallothionein into Protein IX for Analysis of Biodistribution
Using adenovirus (Ad)-based vectors is a promising strategy for novel cancer treatments; however, current tracking approaches in vivo are limited. The C-terminus of the Ad minor capsid protein IX (pIX) can incorporate heterologous reporters to monitor biodistribution. We incorporated metallothionein...
Main Authors: | Lei Liu, Buck E. Rogers, Natalia Aladyshkina, Bing Cheng, Stephen J. Lokitz, David T. Curiel, J. Michael Mathis |
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Format: | Article |
Language: | English |
Published: |
SAGE Publications
2014-09-01
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Series: | Molecular Imaging |
Online Access: | https://doi.org/10.2310/7290.2014.00022 |
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