3,4-Dihydro-3-(2-hydroxyethyl)-4-(nitromethyl)quinazolin-2(1H)-one

3,4-Dihydro-3-(2-hydroxyethyl)-4-(nitromethyl)quinazolin-2(1H)-one

A one-pot, direct synthesis of 3,4-dihydro-3-(2-hydroxyethyl)-4-(nitromethyl)quinazolin-2(1H)-one from o-formylphenyl N-methylcarbamate, ethanolamine and nitromethane in AcOH is reported. The reaction proceeds via a cascade three-component aza-Henry reaction under microwave irradiation and the title...

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Bibliographic Details
Main Authors: Rajiv T. Sawant, Marc Y. Stevens, Luke R. Odell
Format: Article
Language:English
Published: MDPI AG 2015-07-01
Series:Molbank
Subjects:
multicomponent reaction
aza-Henry
3,4-dihydroquinazolinone
Online Access:http://www.mdpi.com/1422-8599/2015/3/M866

Internet

http://www.mdpi.com/1422-8599/2015/3/M866

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