Differential but complementary roles of HIF-1α and HIF-2α in the regulation of bone homeostasis
Abstract Bone is a highly dynamic tissue undergoing continuous formation and resorption. Here, we investigated differential but complementary roles of hypoxia-inducible factor (HIF)-1α and HIF-2α in regulating bone remodeling. Using RNA-seq analysis, we identified that specific genes involved in reg...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2024-07-01
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| Series: | Communications Biology |
| Online Access: | https://doi.org/10.1038/s42003-024-06581-z |