Design and synthesis of various 1,3,4-oxadiazoles as AChE and LOX enzyme inhibitors

Design and synthesis of various 1,3,4-oxadiazoles as AChE and LOX enzyme inhibitors

N-Substituted-2-propanamide analogues of 1,3,4-oxadiazole have been synthesized using a multi-step synthetic protocol to explore new therapeutic anti-enzymatic agents. Herein, we have merged sulfonyl, piperidine, oxadiazole and amide into a single unit to synthesize a library of unique compounds, 8a...

Full description

Bibliographic Details
Main Authors: Iqbal Javed, Mallhi Ali Imran, ur Rehman Aziz, Al-Mijalli Samiah H., un-Nisa Mehr, Zafar Fatiqa, Shahzad Sohail, Rasool Shahid, Iqbal Munawar, Shah Syed Adnan Ali
Format: Article
Language:English
Published: De Gruyter 2023-11-01
Series:Heterocyclic Communications
Subjects:
1,3,4-oxadiazole
piperidine
lipoxygenase
urease
acetyl cholinesterase
Online Access:https://doi.org/10.1515/hc-2022-0169

Internet

https://doi.org/10.1515/hc-2022-0169

Similar Items