Inhibition of pre-mRNA splicing by a synthetic Blom7α-interacting small RNA.

Originally the novel protein Blom7α was identified as novel pre-mRNA splicing factor that interacts with SNEV(Prp19/Pso4), an essential protein involved in extension of human endothelial cell life span, DNA damage repair, the ubiquitin-proteasome system, and pre-mRNA splicing. Blom7α belongs to the...

Full description

Bibliographic Details
Main Authors: Marlies Löscher, Markus Schosserer, Eric Dausse, Kiseok Lee, Paul Ajuh, Regina Grillari-Voglauer, Angus I Lamond, Jean-Jacques Toulmé, Johannes Grillari
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3483155?pdf=render