Research progress of targeted therapy regulating Th17/Treg balance in bone immune diseases

Research progress of targeted therapy regulating Th17/Treg balance in bone immune diseases

Rheumatoid arthritis (RA) and postmenopausal osteoporosis (PMOP) are common bone-immune diseases. The imbalance between helper (Th17) and regulatory T cells (Tregs) produced during differentiation of CD4+ T cells plays a key regulatory role in bone remodelling disorders in RA and PMOP. However, the...

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Bibliographic Details
Main Authors: Xiaxia Wang, Bai Sun, Yujie Wang, Peng Gao, Jiayi Song, Weirong Chang, Zhipan Xiao, Yongbin Xi, Zhonghong Li, Fangyu An, Chunlu Yan
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-01-01
Series:Frontiers in Immunology
Subjects:
rheumatoid arthritis
postmenopausal osteoporosis
targeted therapy
Th17/Treg equilibrium
bone immunity
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1333993/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2024.1333993/full

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