Mechanochemical Synthesis of PdO<sub>2</sub> Nanoparticles Immobilized over Silica Gel for Catalytic Suzuki–Miyaura Cross-Coupling Reactions Leading to the C-3 Modification of 1<i>H</i>-Indazole with Phenylboronic Acids

Mechanochemical Synthesis of PdO<sub>2</sub> Nanoparticles Immobilized over Silica Gel for Catalytic Suzuki–Miyaura Cross-Coupling Reactions Leading to the C-3 Modification of 1<i>H</i>-Indazole with Phenylboronic Acids

The C-3 modification of 1<i>H</i>-indazole has produced active pharmaceuticals for the treatment of cancer and HIV. But, so far, this transformation has seemed less available, due to the lack of efficient C-C bond formation at the less reactive C-3 position. In this work, a series of sil...

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Bibliographic Details
Main Authors: Qin Pan, Yong Wu, Aqun Zheng, Xiangdong Wang, Xiaoyong Li, Wanqin Wang, Min Gao, Zainab Bibi, Sidra Chaudhary, Yang Sun
Format: Article
Language:English
Published: MDPI AG 2023-10-01
Series:Molecules
Subjects:
ball milling
Suzuki–Miyaura cross-coupling
1<i>H</i>-indazole
PdO<sub>2</sub> nanoparticle
silica gel
Online Access:https://www.mdpi.com/1420-3049/28/20/7190

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https://www.mdpi.com/1420-3049/28/20/7190

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