Antibody-platinum (IV) prodrugs conjugates for targeted treatment of cutaneous squamous cell carcinoma

Antibody-platinum (IV) prodrugs conjugates for targeted treatment of cutaneous squamous cell carcinoma

Antibody-drug conjugates (ADCs) are a new type of targeting antibodies that conjugate with highly toxic anticancer drugs via chemical linkers to exert high specificity and efficient killing of tumor cells, thereby attracting considerable attention in precise oncology therapy. Cetuximab (Cet) is a ty...

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Bibliographic Details
Main Authors: Xiangye Yin, Yingjie Zhuang, Haiqin Song, Yujian Xu, Fan Zhang, Jianxin Cui, Lei Zhao, Yingjie Yu, Qixu Zhang, Jun Ye, Youbai Chen, Yan Han
Format: Article
Language:English
Published: Elsevier 2024-03-01
Series:Journal of Pharmaceutical Analysis
Subjects:
Antibody drug conjugate
Cutaneous squamous cell carcinoma
DNA damage
Platinum drug
Targeted therapy
Online Access:http://www.sciencedirect.com/science/article/pii/S2095177923002678

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http://www.sciencedirect.com/science/article/pii/S2095177923002678

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