Biomimetic device and foreign body reaction cooperate for efficient tumour cell capture in murine advanced ovarian cancer

Biomimetic device and foreign body reaction cooperate for efficient tumour cell capture in murine advanced ovarian cancer

Metastasis is facilitated by the formation of pre-metastatic niches through the remodelling of the extracellular matrix (ECM) promoted by haematopoietic and stromal cells. The impact of these primed sites is pronounced for intraperitoneal metastases, where the cavity-exposed ECM supports the attachm...

Full description

Bibliographic Details
Main Authors: Lorena Alonso-Alconada, Alexandre de la Fuente, María Santacana, Alba Ferreiros, Rafael Lopez-Lopez, Xavier Matias-Guiu, Miguel Abal
Format: Article
Language:English
Published: The Company of Biologists 2020-06-01
Series:Disease Models & Mechanisms
Subjects:
biomimetics
foreign body reaction
ovarian cancer
peritoneal metastasis
tumour cell capture
Online Access:http://dmm.biologists.org/content/13/6/dmm043653

Internet

http://dmm.biologists.org/content/13/6/dmm043653

Similar Items