Possible Implication of Nrf2, PPAR-γ and MAPKs Signaling in the Protective Role of Mangiferin against Renal Ischemia/Reperfusion in Rats

Possible Implication of Nrf2, PPAR-γ and MAPKs Signaling in the Protective Role of Mangiferin against Renal Ischemia/Reperfusion in Rats

Mangiferin (Mang) is a known glucosylxanthone that has proven its shielding effect against ischemia/reperfusion (Is/R). However, its full underlying mechanistic perspective against renal Is/R induced lesions is not fully revealed. Consequently, the purpose of this study is to track further non-inves...

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Bibliographic Details
Main Authors: Abdallah M. Gendy, Amira A. El-Gazar, Ghada M. Ragab, Asmaa K. Al-Mokaddem, Alaadin E. El-Haddad, Heba Mohammed Refat M. Selim, Einas Mohamed Yousef, Najat O. Hamed, Sherihan Salaheldin Abdelhamid Ibrahim
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Pharmaceuticals
Subjects:
mangiferin
renal ischemia
Nrf2/HO-1
PPAR-γ/NF-κB
MAPK/JNK
Online Access:https://www.mdpi.com/1424-8247/16/1/6

Internet

https://www.mdpi.com/1424-8247/16/1/6

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