Novel arylazo nicotinate derivatives as effective antibacterial agents: Green synthesis, molecular modeling, and structure-activity relationship studies

Novel arylazo nicotinate derivatives as effective antibacterial agents: Green synthesis, molecular modeling, and structure-activity relationship studies

A series of novel arylazo nicotinates compounds, denoted as (3a-k and 5a-d) were synthesized and characterized through the reaction of 3-oxo-arylhydrazonals with various active methylene nitriles using microporous zeolite as a green catalyst. The structure of the newly prepared heterocycles was dete...

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Bibliographic Details
Main Authors: Mohamed R. Eletmany, Marzough Aziz Albalawi, Reem A.K. Alharbi, Rokaia B. Elamary, Abd El-Fattah A. Harb, Moghraby A. Selim, Asmaa Sayed Abdelgeliel, Entesar A. Hassan, Islam M. Abdellah
Format: Article
Language:English
Published: Elsevier 2023-05-01
Series:Journal of Saudi Chemical Society
Subjects:
Zeolite
Arylazo nicotinates
Antibacterial activity
Density-functional theory (DFT) studies
Structure-activity relationship
Online Access:http://www.sciencedirect.com/science/article/pii/S1319610323000510

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http://www.sciencedirect.com/science/article/pii/S1319610323000510

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