Higher fibrotic content of endometriotic lesions is associated with diminished prostaglandin E2 signaling

Abstract Purpose While the prevailing view holds that the prostaglandin E2 (PGE2) signaling plays a vital role in endometriosis, PGE2 also is known to be anti‐fibrotic. We investigated the immunostaining of COX‐2, EP2, and EP4, along with fibrotic content in ovarian endometrioma (OE) and deep endome...

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Bibliographic Details
Main Authors: Qingqing Huang, Xishi Liu, Sun‐Wei Guo
Format: Article
Language:English
Published: Wiley 2022-01-01
Series:Reproductive Medicine and Biology
Subjects:
Online Access:https://doi.org/10.1002/rmb2.12423